Applied sciences for Viral Vector Manufacturing

Manufacturing of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparability of Platform Applied sciences for Viral Vector Manufacturing

Modified Vaccinia Ankara (MVA) virus is a promising vector for vaccination in opposition to numerous difficult pathogens or the remedy of some kinds of cancers. As a result of this vector is unable to duplicate in human recipients, a excessive quantity of virions per dose is required for vaccination and gene remedy. Upstream course of intensification combining perfusion applied sciences, the avian suspension cell line AGE1.CR.pIX and the virus pressure MVA-CR19 is an choice to acquire very excessive MVA yields.

Right here we in contrast totally different choices for cell retention in perfusion mode utilizing typical stirred-tank bioreactors together with an alternating tangential stream filtration system, an acoustic settler and an inclined settler. The final two choices allowed steady MVA virus harvesting. Moreover, we studied hollow-fiber based mostly bioreactors and an orbital-shaken bioreactor in perfusion mode, each accessible for single-use. Productiveness for the virus pressure MVA-CR19 was in comparison with outcomes from batch and steady manufacturing reported in literature.

Our outcomes display that MVA virus is extremely steady at 37°C in cell tradition in order that cell retention gadgets are solely required to maximise cell focus however not for steady harvesting. Utilizing a stirred-tank bioreactor, a perfusion technique throughout the entire run with working quantity enlargement after virus an infection resulted within the highest yields.

General, infectious MVA virus titers of two.1-16.5 × 109 virions/mL have been achieved in these intensified processes. Taken collectively, the examine exhibits a novel perspective on high-yield MVA virus manufacturing in typical bioreactor methods linked to numerous cell retention gadgets and addresses choices for course of intensification together with absolutely single-use perfusion platforms. This text is protected by copyright. All rights reserved.

resourcerecovery
resourcerecovery

IGF-BP4, human recombinant

7166-10 each
EUR 301.2

IGF-BP4, human recombinant

7166-50 each
EUR 1123.2

Recombinant Human IGF-BP4 Protein

PROTP22692-1 20ug
EUR 380.4
Description: IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway. The biological effects of IGF-BP4 can be regulated by Pregnancy Associated Plasma Protein A (PAPP-A), which reduces IGF-BP4/IGF binding affinity by proteolytically cleaving IGF-BP4. The modulation of IGF-BP4 activity by PAPP-A is an important component in the regulation of ovarian folliculogenesis and in the growth inhibition of responding ovarian cancer cells. Recombinant human IGF-BP4 is a 25.8 kDa protein consisting of 237 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.

*Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

IGF-BP4 Recombinant Protein

40-318-0005mg 0.005 mg
EUR 311.1
Description: IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway. The biological effects of IGF-BP4 can be regulated by Pregnancy Associated Plasma Protein A (PAPP-A), which reduces IGF-BP4/IGF binding affinity by proteolytically cleaving IGF-BP4. The modulation of IGF-BP4 activity by PAPP-A is an important component in the regulation of ovarian folliculogenesis and in the growth inhibition of responding ovarian cancer cells. Recombinant human IGF-BP4 is a 25.8 kDa protein consisting of 237 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.

IGF-BP4 Recombinant Protein

40-318-002mg 0.02 mg
EUR 437.1
Description: IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway. The biological effects of IGF-BP4 can be regulated by Pregnancy Associated Plasma Protein A (PAPP-A), which reduces IGF-BP4/IGF binding affinity by proteolytically cleaving IGF-BP4. The modulation of IGF-BP4 activity by PAPP-A is an important component in the regulation of ovarian folliculogenesis and in the growth inhibition of responding ovarian cancer cells. Recombinant human IGF-BP4 is a 25.8 kDa protein consisting of 237 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.

Recombinant Human IGF BP3

HEGFP-0903 5ug Ask for price

Recombinant Human IGF BP5

HEGFP-0905 5ug Ask for price

Recombinant Human IGF BP7

HEGFP-0907 5ug Ask for price

IGF BP3 antibody

70R-IR022 50 ug
EUR 327.6
Description: Affinity purified Rabbit polyclonal IGF BP3 antibody

IGF BP5 antibody

70R-IR023 50 ug
EUR 327.6
Description: Affinity purified Rabbit polyclonal IGF BP5 antibody

IGF BP7 antibody

70R-IR024 50 ug
EUR 327.6
Description: Affinity purified Rabbit polyclonal IGF BP7 antibody

IGF BP2 protein

30R-AI105 20 ug
EUR 327.6
Description: Purified recombinant Human IGF BP2 protein

IGF BP6 protein

30R-AI106 25 ug
EUR 327.6
Description: Purified recombinant Human IGF BP6 protein

IGF BP7 protein

30R-AI120 25 ug
EUR 327.6
Description: Purified recombinant Human IGF BP7 protein

IGF BP1 protein

30R-AI121 25 ug
EUR 327.6
Description: Purified recombinant Human IGF BP1 protein

IGF BP3 protein

30R-AI122 25 ug
EUR 327.6
Description: Purified recombinant Human IGF BP3 protein

IGF BP5 protein

30R-AI124 25 ug
EUR 327.6
Description: Purified recombinant Human IGF BP5 protein

IGF-BP3, Human

HY-P7020 10ug
EUR 280.8

IGF-BP5, Human

HY-P7021 50ug
EUR 721.2

IGF-BP3, human

RC216-12B3 5ug
EUR 125.26

IGF-1, Human

HY-P7018 10ug
EUR 129.6

IGF-2, Human

HY-P7019 100ug
EUR 432

IGF-1, human

RC216-12 1mg
EUR 451.5

Antibody for Human IGF-1

SPC-699D-ALP 0.1mg
EUR 472.8
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Alkaline Phosphatase.

Antibody for Human IGF-1

SPC-699D-DY350 0.1mg
EUR 496.8
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Dylight 350.

Antibody for Human IGF-1

SPC-699D-DY405 0.1mg
EUR 483.6
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Dylight 405.

Antibody for Human IGF-1

SPC-699D-DY488 0.1mg
EUR 471.6
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Dylight 488.

Antibody for Human IGF-1

SPC-699D 0.1mg
EUR 424.8
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is unconjugated.

Antibody for Human IGF-1

SPC-699D-A390 0.1mg
EUR 481.2
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 390.

Antibody for Human IGF-1

SPC-699D-A488 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 488.

Antibody for Human IGF-1

SPC-699D-A565 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 565.

Antibody for Human IGF-1

SPC-699D-A594 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 594.

Antibody for Human IGF-1

SPC-699D-A633 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 633.

Antibody for Human IGF-1

SPC-699D-A655 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 655.

Antibody for Human IGF-1

SPC-699D-A680 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 680.

Antibody for Human IGF-1

SPC-699D-A700 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 700.

Antibody for Human IGF-1

SPC-699D-APC 0.1mg
EUR 478.8
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to APC .

Antibody for Human IGF-1

SPC-699D-APCCY7 0.1mg
EUR 565.2
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to APC/Cy7.

Antibody for Human IGF-1

SPC-699D-BI 0.1mg
EUR 475.2
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Biotin.

Antibody for Human IGF-1

SPC-699D-DY594 0.1mg
EUR 474
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Dylight 594.

Antibody for Human IGF-1

SPC-699D-DY633 0.1mg
EUR 468
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Dylight 633.

Antibody for Human IGF-1

SPC-699D-FITC 0.1mg
EUR 470.4
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to FITC.

Antibody for Human IGF-1

SPC-699D-HRP 0.1mg
EUR 465.6
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to HRP.

Antibody for Human IGF-1

SPC-699D-P594 0.1mg
EUR 488.4
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to PE/ATTO 594.

Antibody for Human IGF-1

SPC-699D-PCP 0.1mg
EUR 478.8
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to PerCP.

Antibody for Human IGF-1

SPC-699D-RPE 0.1mg
EUR 476.4
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to RPE .

Antibody for Human IGF-1

SPC-699D-STR 0.1mg
EUR 477.6
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Streptavidin.

Antibody for Human IGF-1

SPC-699S 0.012mg
EUR 78
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is unconjugated.

Human Salivary IGF(salivary IGF) ELISA Kit

QY-E05383 96T
EUR 433.2

Human IGF-1 LR3

SP-89927-100 100 ug
EUR 270

IGF-BP2, human recombinant

7165-10 each
EUR 301.2

IGF-BP2, human recombinant

7165-50 each
EUR 1123.2

IGF-BP7, human recombinant

7167-10 each
EUR 248.4

IGF-BP7, human recombinant

7167-50 each
EUR 810

IGF-BP6, human recombinant

7350-20 each
EUR 444

IGF-BP1, human recombinant

4717-100 each
EUR 744

IGF-BP1, human recombinant

4717-1000 each
EUR 3778.8

IGF-BP1, human recombinant

4717-25 each
EUR 307.2

IGF-BP3, human recombinant

4720-100 each
EUR 744

IGF-BP3, human recombinant

4720-1000 each
EUR 3778.8

IGF-BP3, human recombinant

4720-25 each
EUR 307.2

IGF-BP5, human recombinant

4723-100 each
EUR 744

IGF-BP5, human recombinant

4723-1000 each
EUR 3778.8

IGF-BP5, human recombinant

4723-25 each
EUR 307.2

Recombinant Human IGF-1

HEGFP-0901 100ug Ask for price

Recombinant Human IGF-2

HEGFP-0908 10ug Ask for price

Anti-Rat IGF-1 Antibody

5121-100 each
EUR 379.2

Anti-Rat IGF-1 Antibody

5121-30T each
EUR 175.2

Human IGF-I monoclonal antibody

MAM1 500 µg
EUR 358.8

IGF-1, human recombinant

P1016-.02 20 µg
EUR 309.6
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue

IGF-1, human recombinant

P1016-.1 100 µg
EUR 915.6
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue

rec IGF-I (human)

H-5555.0050 50.0µg
EUR 290.4
Description: CAS# [67763-96-6]

rec IGF-I (human)

H-5555.0100 100.0µg
EUR 457.2
Description: CAS# [67763-96-6]

rec IGF-I (human)

H-5555.0500 0.5mg
EUR 1720.8
Description: CAS# [67763-96-6]

Human IGF-I Protein

abx060791-100ug 100 ug
EUR 560.4

Biotinyl Human IGF-I

AQU010 10 µg
EUR 303.6

Biotinyl Human IGF-I

AQU050 50 µg
EUR 415.2

Biotinyl Human IGF-I

AQU100 100 µg
EUR 637.2

Biotinyl Human IGF-I

AQU500 500 µg
EUR 1305.6

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-1mg

QP8601-ec-1mg 1mg
EUR 1958.4

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-10ug

QP8601-ec-10ug 10ug
EUR 240

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-50ug

QP8601-ec-50ug 50ug
EUR 315.6

Human [Ala31] IGF-I

AIU020 20 µg
EUR 303.6

Human [Ala31] IGF-I

AIU100 100 µg
EUR 415.2

Human [Leu60] IGF-I

ABU020 20 µg
EUR 303.6

Human [Leu60] IGF-I

ABU100 100 µg
EUR 415.2

Human [Arg6] IGF-II

GU020 20 µg
EUR 303.6

Human [Leu24] IGF-I

ZU020 20 µg
EUR 303.6

Human [Leu24] IGF-I

ZU100 100 µg
EUR 415.2

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-100ug

QP8601-ec-100ug 100ug
EUR 489.6

Mosaic Recombinant Adeno-associated Virus Vector rAAV/DJ/CAG for Focused Gene Supply to Melanoma Cells Metastasized to the Lung

Background/goal: Sufferers with metastasized melanoma have restricted remedy choices and poor analysis. Subsequently, the event of therapies requires a brand new therapeutic strategy, of which gene remedy utilizing rAAV vectors might be proposed. The goal of the examine was to look at the effectivity of the rAAV vector to transduce mouse melanoma cells each in vitro and in vivo.

Supplies and strategies: Totally different rAAV serotypes encoding GFP underneath the management of each hen beta-actin and cytomegalovirus promoters have been used within the experiments. Intranasal, intraperitoneal, intravenous and intratumoral pathways of administration of rAAV vectors have been examined utilizing quantitative-PCR and immunohistochemical staining.

Outcomes: The very best transduction effectivity in metastatic cells in vivo was noticed 7 days after intranasal administration of a 1010 gc/0.03 ml dose of rAAV/DJ-CAG.

Conclusion: Melanoma gene remedy based mostly on rAAV vectors is a attainable remedy possibility.

Vector Competence of Aedes aegypti, Aedes albopictus and Culex quinquefasciatus from Brazil and New Caledonia for Three Zika Virus Lineages

Zika virus (ZIKV) has prompted extreme epidemics in South America starting in 2015, following its unfold via the Pacific. We comparatively assessed the vector competence of ten populations of Aedes aegypti and Ae. albopictus from Brazil and two of Ae. aegypti and one in all Culex quinquefasciatus from New Caledonia to transmit three ZIKV isolates belonging to African, Asian and American lineages.

Just lately colonized mosquitoes from eight distinct websites from each international locations have been orally challenged with the identical viral load (107 TCID50/mL) and examined after 7, 14 and 21 days. Cx. quinquefasciatus was refractory to an infection with all virus strains. In distinction, though competence assorted with geographical origin, Brazilian and New Caledonian Ae. aegypti may transmit the three ZIKV lineages, with a robust benefit for the African lineage (the one one reaching saliva one-week after problem).

Brazilian Ae. albopictus populations have been much less competent than Ae. aegypti populations. Ae. albopictus usually exhibited nearly no transmission for Asian and American lineages, however was environment friendly in transmitting the African ZIKV. Viral surveillance and mosquito management measures should be strengthened to keep away from the unfold of latest ZIKV lineages and decrease the transmission of viruses at the moment circulating.

Anti-IL-8 Antibody
A00423 1 mL
EUR 1444.8
Description: Rabbit Polyclonal IL-8 Antibody. Validated in IP, WB and tested in Human.
Anti-IL-8 antibody
STJ97710 200 µl
EUR 236.4
Description: Mouse monoclonal to IL-8.
Anti-IL-8 antibody
STJ97717 200 µl
EUR 236.4
Description: Mouse monoclonal to IL-8.
Anti-IL-8 antibody
STJ97720 200 µl
EUR 236.4
Description: Mouse monoclonal to IL-8.
Anti-IL-8 antibody
STJ98175 100 µl
EUR 280.8
Description: Mouse monoclonal to IL-8.
anti-IL-8 (3E4D8)
LF-MA30011 100 ul
EUR 448.8
Description: Mouse Monoclonal to IL-8
mAb mouse anti-human IL-8
CT264 0.5 mg
EUR 312
IL-8/CXCL8, Human
HY-P7224 50ug
EUR 596.4
Human IL-8 Protein
abx060803-25ug 25 ug
EUR 644.4
Human IL-8 Protein
abx060804-25ug 25 ug
EUR 644.4
Recombinant Human IL-8
P0180 100ug
EUR 626.83
Description: Recombinant Human protein for IL-8
Recombinant Human IL-8
SJB05-01 25µg/vial
EUR 342
Rabbit anti-IL-8 Antibody
DL90596A-100ul 100 ul
EUR 270
Description: CXCL8; Interleukin-8; IL-8; C-X-C motif chemokine 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor
Rabbit anti-IL-8 Antibody
DL90596A-50ul 50 ul
EUR 189
Description: CXCL8; Interleukin-8; IL-8; C-X-C motif chemokine 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor
Anti-IL-8 Monoclonal Antibody
A00423-1 100ul
EUR 476.4
Description: Mouse Monoclonal Antibody for IL-8 Antibody (CXCL8) detection. Tested with IHC in Human, Mouse, Rat.
Human Interleukin-8 (IL-8) Antibody (Biotin Conjugate)
13102-05021 150 ug
EUR 313.2
Human IL-8 ELISA antibody pair
CT748-10 10-plate
EUR 656.4
Human IL-8 ELISA antibody pair
CT748-20 20-plate
EUR 1118.4
Human IL-8 Antibody (Biotin Conjugate)
33486-05121 150 ug
EUR 442.8
Human Interleukin 8 (IL-8) CLIA Kit
abx195916-96tests 96 tests
EUR 990
Human Interleukin 8,IL-8 ELISA KIT
201-12-0090 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
Human Interleukin 8, IL-8 ELISA KIT
CSB-E04641h-24T 1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Human Interleukin 8, IL-8 in samples from serum, cell culture supernates, saliva, urine, cerebrospinalfluid (CSF), tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Human Interleukin 8, IL-8 ELISA KIT
1-CSB-E04641h
  • EUR 600.00
  • EUR 4082.40
  • EUR 2184.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human Interleukin 8, IL-8 in samples from serum, cell culture supernates, saliva, urine, cerebrospinalfluid(CSF), tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Human Interleukin 8(IL-8)ELISA Kit
GA-E0129HM-48T 48T
EUR 346.8
Human Interleukin 8(IL-8)ELISA Kit
GA-E0129HM-96T 96T
EUR 559.2
Human IL-8(Interleukin 8) ELISA Kit
EH0205 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml
Human Interleukin 8(IL-8)ELISA Kit
QY-E04259 96T
EUR 433.2
Human Interleukin 8,IL-8 ELISA KIT
YLA1210HU-48T 48T
EUR 435
Human Interleukin 8,IL-8 ELISA KIT
YLA1210HU-96T 96T
EUR 562.5
Human Interleukin-8 (IL-8) ELISA Kit
LF-EK60006 1×96T
EUR 948
human IL-8 His tag
E410A07-100 100μg
EUR 1152
Human IL-8 ELISA kit
CT212A 5-plate
EUR 554.4
Human IL-8 ELISA kit
LF-EK50165 1×96T
EUR 777.6
IL-8 ELISA KIT|Human
EF003990 96 Tests
EUR 826.8
Human IL-8 ELISA Kit
EHI0063 96Tests
EUR 625.2
IL-8/CXCL8, 72a.a., Human
HY-P7380 50ug
EUR 596.4
IL-8 (Human) ELISA Kit
K4169-100 each
EUR 874.8
Human Interleukin-8 (IL-8) AssayLite Antibody (RPE Conjugate)
13102-05051 150 ug
EUR 513.6
Human Interleukin-8 (IL-8) AssayLite Antibody (APC Conjugate)
13102-05061 150 ug
EUR 513.6
Human Interleukin-8 (IL-8) AssayLite Antibody (FITC Conjugate)
13102-05041 150 ug
EUR 513.6
rec Monocyte IL-8 (human)
H-9625.0005 5.0µg
EUR 194.4
Description: Sum Formula: C372H600N106O106S4; CAS# [142298-00-8]
rec Monocyte IL-8 (human)
H-9625.0025 25.0µg
EUR 457.2
Description: Sum Formula: C372H600N106O106S4; CAS# [142298-00-8]
Human Interleukin-8 (IL-8) AssayLite Antibody (PerCP Conjugate)
13102-05071 150 ug
EUR 565.2
rec Endothelial IL-8 (human)
H-3742.0010 10.0µg
EUR 340.8
Description: Sum Formula: C397H644N114O111S4; CAS# [142298-01-9]
rec Endothelial IL-8 (human)
H-3742.0050 50.0µg
EUR 1167.6
Description: Sum Formula: C397H644N114O111S4; CAS# [142298-01-9]
Recombinant Human IL-8 (72a.a.)
HEILP-0801 5ug Ask for price
Recombinant Human IL-8 (77a.a.)
HEILP-0802 5ug Ask for price
Recombinant Human IL-8 Protein
RP00052 5 μg
EUR 178.8
Human IL-8 Recombinant Protein
R00423-8 5ug/vial
EUR 310.8
Description: Interleukin-8 (IL-8), also known as CXCL8, is an ELR-positive CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. Human IL-8 Recombinant Protein is purified interleukin-8 produced in yeast.
Anti-bovine IL-8 (CXCL8) antibody
STJ15100008 250 µg
EUR 403.2
Description: These monoclonal antibodies enable sensitive and specific detection of bovine IL-8 in ELISpot.
Anti-bovine IL-8 (CXCL8) antibody
STJ15100009 250 µg
EUR 403.2
Description: This monoclonal antibody enables sensitive and specific detection of bovine IL-8 in ELISA.
CLIA kit for Human IL-8 (Interleukin 8)
E-CL-H0048 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human IL-8 (Interleukin 8) in samples from Serum, Plasma, Cell supernatant
IL-8, CXCL8, Interleukin-8 (72 a.a.), human
RC212-19A 5ug
EUR 125.26
IL-8, CXCL8, Interleukin-8 (77 a.a.), human
RC212-19B 5ug
EUR 125.26
ELISA kit for Human IL-8 (Interleukin 8)
E-EL-H0048 1 plate of 96 wells
EUR 452.4
Description: A sandwich ELISA kit for quantitative measurement of Human IL-8 (Interleukin 8) in samples from Serum, Plasma, Cell supernatant
ELISA kit for Human Interleukin 8,IL-8
EK0240 96 tests
EUR 723.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Interleukin 8,IL-8 in samples from serum, plasma, tissue homogenates and other biological fluids.
IL-8 Antibody
BF0238 200ul
EUR 540
IL-8 Antibody
5149-100 each
EUR 405.6
IL-8 Antibody
F51235-0.08ML 0.08 ml
EUR 140.25
Description: IL8 is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor.
IL-8 Antibody
F51235-0.4ML 0.4 ml
EUR 322.15
Description: IL8 is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor.
IL-8 Antibody
R30420 100 ug
EUR 356.15
Description: Interleukin-8(IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene. Interleukin-8(IL8) is a member of the CXC chemokine family(Hull et al., 2001). IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. The genes for IL8 have been co-localized on a 335-kb genomic fragment.
IL-8 Antibody
R31932 100 ug
EUR 356.15
Description: Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene. Interleukin-8 (IL8) is a member of the CXC chemokine family. IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. The genes for IL8 have been co-localized on a 335-kb genomic fragment.
Human Interleukin-8 (IL-8) AssayMax ELISA Kit
EI1008-1 96 Well Plate
EUR 572.4
Human IL-8 AssayLite Antibody (RPE Conjugate)
33486-05151 150 ug
EUR 513.6
Human IL-8 AssayLite Antibody (APC Conjugate)
33486-05161 150 ug
EUR 513.6
Recombinant Human Interleukin-8/IL-8 (C-6His)
CC97-10ug 10ug
EUR 175.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Recombinant Human Interleukin-8/IL-8 (C-6His)
CC97-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Recombinant Human Interleukin-8/IL-8 (C-6His)
CC97-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Recombinant Human Interleukin-8/IL-8 (C-6His)
CC97-50ug 50ug
EUR 406.8
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Human IL-8 AssayLite Antibody (FITC Conjugate)
70021-05141 150 ug
EUR 513.6
Human IL-8 AssayLite Antibody (FITC Conjugate)
33486-05141 150 ug
EUR 513.6
Human IL-8 AssayLite Antibody (PerCP Conjugate)
33486-05171 150 ug
EUR 565.2
Recombinant Human Interleukin-8/IL-8 (Ser28-Ser99)
C035-10ug 10ug
EUR 181.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Recombinant Human Interleukin-8/IL-8 (Ser28-Ser99)
C035-1mg 1mg
EUR 2203.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Recombinant Human Interleukin-8/IL-8 (Ser28-Ser99)
C035-500ug 500ug
EUR 1557.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Recombinant Human Interleukin-8/IL-8 (Ser28-Ser99)
C035-50ug 50ug
EUR 424.8
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Recombinant Human Interleukin-8/IL-8 (Ala23-Ser99)
C037-10ug 10ug
EUR 181.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Recombinant Human Interleukin-8/IL-8 (Ala23-Ser99)
C037-1mg 1mg
EUR 2203.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Recombinant Human Interleukin-8/IL-8 (Ala23-Ser99)
C037-500ug 500ug
EUR 1557.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Recombinant Human Interleukin-8/IL-8 (Ala23-Ser99)
C037-50ug 50ug
EUR 412.8
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
IL-8
E5-00004 1mg
EUR 1152
ELISA kit for Human IL-8
KET6018-48T 48T
EUR 242.4
Description: Quantitative sandwich ELISA for measuring Human IL-8 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human IL-8
KET6018-5platesof96wells 5 plates of 96 wells
EUR 1292.4
Description: Quantitative sandwich ELISA for measuring Human IL-8 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human IL-8
KET6018-96T 96T
EUR 346.8
Description: Quantitative sandwich ELISA for measuring Human IL-8 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Human IL-8 ELISA kit (4X96T)
LF-EK50166 4×96T
EUR 2641.2
Human IL-8/CXCL8 ELISA Kit
RK00011 96 Tests
EUR 625.2
IL-8 (77 a.a.), human recombinant
4149-1000 each
EUR 4758
IL-8 (77 a.a.), human recombinant
4149-25 each
EUR 339.6
IL-8 (72 a.a.), human recombinant
4149M-1000 each
EUR 4758
IL-8 (72 a.a.), human recombinant
4149M-25 each
EUR 339.6
CymaxTM Human IL-8 ELISA Kit
LF-EK0262 1×96T
EUR 477.6
IL-8 (77 a.a.), human recombinant
P1026-.025 25 µg
EUR 360
Description: Interleukin-8 (IL-8) is a proinflammatory CXC chemokine produced by macrophages, epithelial cells. IL-8 is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies
IL-8 (77 a.a.), human recombinant
P1026-1 1 mg
EUR 5071.2
Description: Interleukin-8 (IL-8) is a proinflammatory CXC chemokine produced by macrophages, epithelial cells. IL-8 is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies
Human IL-8 PicoKine ELISA Kit
EK0413 96 wells
EUR 510
Description: For quantitative detection of human IL-8 in cell culture supernates, serum and plasma(heparin, EDTA, citrate).
IL-8 ELISA Kit (Human) (OKBB00192)
OKBB00192 96 Tests
EUR 606
Description: Description of target: Interleukin-8, also called neutrophil-activating peptide-1 or SCYB8, is a tissue-derived peptide secreted by several types of cells in response to inflammatory stimuli. Monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8, suggested gene symbol IL8) is a cytokine that chemoattracts and activates neutrophils.1 IL-8 is produced and released from human adipose tissue and from isolated adipocytes in vitro, which may indicate that IL-8 from adipose tissue could be involved in some of the obesity-related complications.2 The MDNCF/IL-8 gene is placed on the human gene map at position 4q12-q21. This is the same location where at least three other members (platelet factor 4, melanoma growth stimulatory activity, and interferon-gamma induced factor) of the platelet factor 4 gene superfamily reside.1 Human IL-8 consists of 99 amino acids in precursor form and 79 amino acids in mature form.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 1 pg/ml
IL-8/CXCL8 (CHO-expressed), Human
HY-P7379 50ug
EUR 596.4
Genorise® Recombinant human IL-8
GR104177 5 µg
EUR 285
Genorise® Biotinylated Anti-Human IL-8 Polyclonal Antibody
GR109009 50 mg
EUR 398
Polyclonal IL-8 Antibody
APR00274G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IL-8 . This antibody is tested and proven to work in the following applications:
IL-8 Polyclonal Antibody
41063-100ul 100ul
EUR 302.4
IL-8 Polyclonal Antibody
41063-50ul 50ul
EUR 224.4
IL-8 Polyclonal Antibody
ABP51621-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
IL-8 Polyclonal Antibody
ABP51621-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
IL-8 Polyclonal Antibody
ABP51621-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
IL-8 Polyclonal Antibody
ABP54886-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
IL-8 Polyclonal Antibody
ABP54886-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
IL-8 Polyclonal Antibody
ABP54886-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
IL-8 Polyclonal Antibody
ABP52884-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human IL-8
IL-8 Polyclonal Antibody
ABP52884-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human IL-8
IL-8 Polyclonal Antibody
ABP52884-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human IL-8
IL-8 Polyclonal Antibody
ES3883-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against IL-8 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA
IL-8 Polyclonal Antibody
ES3883-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against IL-8 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA
IL-8 Polyclonal Antibody
ES2620-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against IL-8 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA
IL-8 Polyclonal Antibody
ES2620-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against IL-8 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA
IL-8 Polyclonal Antibody
ES5885-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against IL-8 from Human. This antibody is tested and validated for IHC, WB, ELISA