Manufacturing of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparability of Platform Applied sciences for Viral Vector Manufacturing
Modified Vaccinia Ankara (MVA) virus is a promising vector for vaccination in opposition to numerous difficult pathogens or the remedy of some kinds of cancers. As a result of this vector is unable to duplicate in human recipients, a excessive quantity of virions per dose is required for vaccination and gene remedy. Upstream course of intensification combining perfusion applied sciences, the avian suspension cell line AGE1.CR.pIX and the virus pressure MVA-CR19 is an choice to acquire very excessive MVA yields.
Right here we in contrast totally different choices for cell retention in perfusion mode utilizing typical stirred-tank bioreactors together with an alternating tangential stream filtration system, an acoustic settler and an inclined settler. The final two choices allowed steady MVA virus harvesting. Moreover, we studied hollow-fiber based mostly bioreactors and an orbital-shaken bioreactor in perfusion mode, each accessible for single-use. Productiveness for the virus pressure MVA-CR19 was in comparison with outcomes from batch and steady manufacturing reported in literature.
Our outcomes display that MVA virus is extremely steady at 37°C in cell tradition in order that cell retention gadgets are solely required to maximise cell focus however not for steady harvesting. Utilizing a stirred-tank bioreactor, a perfusion technique throughout the entire run with working quantity enlargement after virus an infection resulted within the highest yields.
General, infectious MVA virus titers of two.1-16.5 × 109 virions/mL have been achieved in these intensified processes. Taken collectively, the examine exhibits a novel perspective on high-yield MVA virus manufacturing in typical bioreactor methods linked to numerous cell retention gadgets and addresses choices for course of intensification together with absolutely single-use perfusion platforms. This text is protected by copyright. All rights reserved.

![]() IGF-BP4, human recombinant |
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7166-50 | Biovision | each | EUR 1123.2 |
![]() IGF-BP4 Recombinant Protein |
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40-318-0005mg | ProSci | 0.005 mg | EUR 311.1 |
Description: IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway. The biological effects of IGF-BP4 can be regulated by Pregnancy Associated Plasma Protein A (PAPP-A), which reduces IGF-BP4/IGF binding affinity by proteolytically cleaving IGF-BP4. The modulation of IGF-BP4 activity by PAPP-A is an important component in the regulation of ovarian folliculogenesis and in the growth inhibition of responding ovarian cancer cells. Recombinant human IGF-BP4 is a 25.8 kDa protein consisting of 237 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain. |
![]() IGF-BP4 Recombinant Protein |
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40-318-002mg | ProSci | 0.02 mg | EUR 437.1 |
Description: IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway. The biological effects of IGF-BP4 can be regulated by Pregnancy Associated Plasma Protein A (PAPP-A), which reduces IGF-BP4/IGF binding affinity by proteolytically cleaving IGF-BP4. The modulation of IGF-BP4 activity by PAPP-A is an important component in the regulation of ovarian folliculogenesis and in the growth inhibition of responding ovarian cancer cells. Recombinant human IGF-BP4 is a 25.8 kDa protein consisting of 237 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain. |
![]() Recombinant Human IGF-BP4 Protein |
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PROTP22692-1 | BosterBio | 20ug | EUR 380.4 |
Description: IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway. The biological effects of IGF-BP4 can be regulated by Pregnancy Associated Plasma Protein A (PAPP-A), which reduces IGF-BP4/IGF binding affinity by proteolytically cleaving IGF-BP4. The modulation of IGF-BP4 activity by PAPP-A is an important component in the regulation of ovarian folliculogenesis and in the growth inhibition of responding ovarian cancer cells. Recombinant human IGF-BP4 is a 25.8 kDa protein consisting of 237 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain. *Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc. |
![]() Human Insulin Like Growth Factor 1 (IGF-1) ELISA Kit, 96 tests, quantitative |
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100-600-IGF | Alpha Diagnostics | 1 kit | EUR 854.4 |
![]() Mouse Insulin Like Growth Factor 1 (IGF-1) ELISA Kit, 96 tests, quantitative |
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100-605-IGF | Alpha Diagnostics | 1 kit | EUR 854.4 |
![]() Rat Insulin Like Growth Factor 1 (IGF-1) ELISA Kit, 96 tests, quantitative |
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100-610-IGF | Alpha Diagnostics | 1 kit | EUR 854.4 |
![]() Rabbit Polyclonal antibody Anti-CRBN |
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Anti-CRBN | ImmunoStep | 50 µg | EUR 418.8 |
![]() Anti-IGF-IR antibody |
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STJ93647 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: IGF-IR is a protein encoded by the IGF1R gene which is approximately 154,7 kDa. IGF-IR is localised to the cell membrane. It is involved in apoptotic pathways, the GPCR pathway and ERK signalling. It is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1. The activated protein is involved in cell growth and survival control and is also crucial for tumour transformation and survival of malignant cells. It is formed from two subunits, each of which is comprised of an extracellular alpha-subunit and a transmembrane beta-subunit with intracellular tyrosine kinase activity. IGF-IR is expressed in the nervous system, skin, pancreas, lung and muscle. Mutations in the IGF1R gene may result in insulin-like growth factor 1 resistance. STJ93647 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of IGF-IR protein. |
![]() Anti-IGF-IR antibody |
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STJ93648 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to IGF-IR. |
![]() Anti-IGF-I antibody |
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STJ93653 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to IGF-I. |
![]() Anti-IGF-IIR antibody |
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STJ93654 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to IGF-IIR. |
![]() Anti-IGF-IIR antibody |
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STJ93655 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to IGF-IIR. |
![]() Anti-IGF-IR antibody |
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STJ93656 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to IGF-IR. |
![]() Anti-IGF-IR antibody |
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STJ93657 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to IGF-IR. |
![]() Anti-IGF-IR antibody |
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STJ98158 | St John's Laboratory | 100 µl | EUR 280.8 |
Description: Mouse monoclonal to IGF-IR. |
![]() Anti-IGF-IR antibody |
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STJ98159 | St John's Laboratory | 100 µl | EUR 280.8 |
Description: Mouse monoclonal to IGF-IR. |
![]() Anti-IGF-IIR antibody |
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STJ96634 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to IGF-IIR. |
![]() Polyclonal Goat anti-GST α-form |
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GST-ANTI-1 | Detroit R&D | 50 uL | EUR 336 |
![]() Polyclonal Goat anti-GST μ-form |
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GST-ANTI-2 | Detroit R&D | 50 uL | EUR 336 |
![]() Polyclonal Goat anti-GST p-form |
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GST-ANTI-3 | Detroit R&D | 50 uL | EUR 336 |
![]() Human Salivary IGF(salivary IGF) ELISA Kit |
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QY-E05383 | Qayee Biotechnology | 96T | EUR 433.2 |
![]() IGF-1, Human |
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HY-P7018 | MedChemExpress | 10ug | EUR 129.6 |
![]() IGF-2, Human |
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HY-P7019 | MedChemExpress | 100ug | EUR 432 |
![]() IGF-BP3, Human |
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HY-P7020 | MedChemExpress | 10ug | EUR 280.8 |
![]() IGF-BP5, Human |
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HY-P7021 | MedChemExpress | 50ug | EUR 721.2 |
![]() IGF-1, human |
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RC216-12 | Bio Basic | 1mg | EUR 451.5 |
![]() IGF-BP3, human |
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RC216-12B3 | Bio Basic | 5ug | EUR 125.26 |
![]() anti-IGF-1R (Ab-1280) |
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LF-PA20229 | Abfrontier | 100 ul | EUR 400.8 |
Description: Rabbit polyclonal to IGF-1R |
![]() anti-IGF-1R (Ab-1346) |
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LF-PA20230 | Abfrontier | 100 ul | EUR 400.8 |
Description: Rabbit polyclonal to IGF-1R |
![]() anti-IGF-1R (Ab-1161) |
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LF-PA20231 | Abfrontier | 100 ul | EUR 400.8 |
Description: Rabbit polyclonal to IGF-1R |
![]() anti-IGF-1R (Phospho-Tyr1161) |
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LF-PA20233 | Abfrontier | 100 ul | EUR 424.8 |
Description: Rabbit polyclonal to IGF-1R (Phospho-Tyr1161) |
![]() Anti-Rat IGF-1 Antibody |
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5121-100 | Biovision | each | EUR 379.2 |
![]() Anti-Rat IGF-1 Antibody |
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5121-30T | Biovision | each | EUR 175.2 |
![]() Anti-IGF-1R (Teprotumumab), Human IgG1 Antibody |
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A2160-100 | Biovision | 100 µg | EUR 612 |
![]() Anti-IGF-1R (Ab-1161) Antibody |
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A00070-1 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal IGF-1R (Ab-1161) Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
![]() Polyclonal Anti-Rat IGF-1 Antibody |
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APR00269G | Leading Biology | 0.1mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Anti-Rat IGF-1 . This antibody is tested and proven to work in the following applications: |
![]() anti-IGF-1R (Ab-1165/1166) |
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LF-PA20232 | Abfrontier | 100 ul | EUR 400.8 |
Description: Rabbit polyclonal to IGF-1R |
![]() anti-IGF-1R (Phospho-Tyr1165/Tyr1166) |
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LF-PA20234 | Abfrontier | 100 ul | EUR 424.8 |
Description: Rabbit polyclonal to IGF-1R (Phospho-Tyr1165/Tyr1166) |
![]() Anti-Phospho-IGF-IR (Y1161) antibody |
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STJ90298 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to Phospho-IGF-IR (Y1161). |
![]() Anti-Phospho-IGF-IIR (S2409) antibody |
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STJ90923 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to Phospho-IGF-IIR (S2409). |
![]() Anti-Phospho-IGF-IR (Y1161) antibody |
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STJ91026 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to Phospho-IGF-IR (Y1161). |
![]() Anti-Phospho-IGF-IR (Y1346) antibody |
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STJ91187 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to Phospho-IGF-IR (Y1346). |
![]() Human IGF-I Protein |
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abx060791-100ug | Abbexa | 100 ug | EUR 560.4 |
![]() Human [Leu60] IGF-I |
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ABU020 | GroPep | 20 µg | EUR 303.6 |
![]() Human [Leu60] IGF-I |
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ABU100 | GroPep | 100 µg | EUR 415.2 |
![]() Human [Ala31] IGF-I |
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AIU020 | GroPep | 20 µg | EUR 303.6 |
![]() Human [Ala31] IGF-I |
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AIU100 | GroPep | 100 µg | EUR 415.2 |
![]() Biotinyl Human IGF-I |
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AQU010 | GroPep | 10 µg | EUR 303.6 |
![]() Biotinyl Human IGF-I |
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AQU050 | GroPep | 50 µg | EUR 415.2 |
![]() Biotinyl Human IGF-I |
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AQU100 | GroPep | 100 µg | EUR 637.2 |
![]() Biotinyl Human IGF-I |
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AQU500 | GroPep | 500 µg | EUR 1305.6 |
![]() IGF-1, human recombinant |
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P1016-.02 | ApexBio | 20 µg | EUR 309.6 |
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue |
![]() IGF-1, human recombinant |
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P1016-.1 | ApexBio | 100 µg | EUR 915.6 |
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue |
![]() IGF-II, human recombinant |
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P1017-.01 | ApexBio | 10 µg | EUR 193.2 |
Description: Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family. |
![]() IGF-II, human recombinant |
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P1017-.05 | ApexBio | 50 µg | EUR 375.6 |
Description: Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family. |
![]() IGF-II, human recombinant |
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P1017-1 | ApexBio | 1 mg | EUR 2397.6 |
Description: Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family. |
![]() rec IGF-I (human) |
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H-5555.0050 | Bachem | 50.0µg | EUR 290.4 |
Description: CAS# [67763-96-6] |
![]() rec IGF-I (human) |
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H-5555.0100 | Bachem | 100.0µg | EUR 457.2 |
Description: CAS# [67763-96-6] |
![]() rec IGF-I (human) |
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H-5555.0500 | Bachem | 0.5mg | EUR 1720.8 |
Description: CAS# [67763-96-6] |
![]() Human [Arg6] IGF-II |
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GU020 | GroPep | 20 µg | EUR 303.6 |
![]() Human IGF-1 LR3 |
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SP-89927-100 | Alpha Diagnostics | 100 ug | EUR 270 |
![]() Human [Leu27]IGF-II |
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TU100 | GroPep | 100 µg | EUR 415.2 |
![]() Human [Leu24] IGF-I |
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ZU020 | GroPep | 20 µg | EUR 303.6 |
![]() Human [Leu24] IGF-I |
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ZU100 | GroPep | 100 µg | EUR 415.2 |
![]() IGF-BP2, human recombinant |
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7165-10 | Biovision | each | EUR 301.2 |
![]() IGF-BP2, human recombinant |
|||
7165-50 | Biovision | each | EUR 1123.2 |
![]() IGF-BP7, human recombinant |
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7167-10 | Biovision | each | EUR 248.4 |
![]() IGF-BP7, human recombinant |
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7167-50 | Biovision | each | EUR 810 |
![]() IGF-BP6, human recombinant |
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7350-20 | Biovision | each | EUR 444 |
![]() IGF-I, human recombinant |
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4119-100 | Biovision | each | EUR 210 |
![]() IGF-I, human recombinant |
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4119-1000 | Biovision | each | EUR 411.6 |
![]() IGF-I, human recombinant |
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4119-10MG | Biovision | each | EUR 1834.8 |
![]() IGF-I, human recombinant |
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4119-1G | Biovision | each | EUR 49388.4 |
![]() IGF-I, human recombinant |
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4119-20MG | Biovision | each | EUR 2793.6 |
![]() IGF-I, human recombinant |
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4119-5000 | Biovision | each | EUR 1149.6 |
![]() IGF-I, human recombinant |
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4119-50MG | Biovision | each | EUR 5064 |
![]() IGF-II, human recombinant |
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4122-10 | Biovision | each | EUR 164.4 |
![]() IGF-II, human recombinant |
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4122-1000 | Biovision | each | EUR 1886.4 |
![]() IGF-II, human recombinant |
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4122-50 | Biovision | each | EUR 307.2 |
![]() IGF-BP1, human recombinant |
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4717-100 | Biovision | each | EUR 744 |
![]() IGF-BP1, human recombinant |
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4717-1000 | Biovision | each | EUR 3778.8 |
![]() IGF-BP1, human recombinant |
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4717-25 | Biovision | each | EUR 307.2 |
![]() IGF-BP3, human recombinant |
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4720-100 | Biovision | each | EUR 744 |
![]() IGF-BP3, human recombinant |
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4720-1000 | Biovision | each | EUR 3778.8 |
![]() IGF-BP3, human recombinant |
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4720-25 | Biovision | each | EUR 307.2 |
![]() IGF-BP5, human recombinant |
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4723-100 | Biovision | each | EUR 744 |
![]() IGF-BP5, human recombinant |
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4723-1000 | Biovision | each | EUR 3778.8 |
![]() IGF-BP5, human recombinant |
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4723-25 | Biovision | each | EUR 307.2 |
![]() IGF-II |
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PR15045CF | Neuromics | 50 ug | EUR 333.6 |
Mosaic Recombinant Adeno-associated Virus Vector rAAV/DJ/CAG for Focused Gene Supply to Melanoma Cells Metastasized to the Lung
Background/goal: Sufferers with metastasized melanoma have restricted remedy choices and poor analysis. Subsequently, the event of therapies requires a brand new therapeutic strategy, of which gene remedy utilizing rAAV vectors might be proposed. The goal of the examine was to look at the effectivity of the rAAV vector to transduce mouse melanoma cells each in vitro and in vivo.
Supplies and strategies: Totally different rAAV serotypes encoding GFP underneath the management of each hen beta-actin and cytomegalovirus promoters have been used within the experiments. Intranasal, intraperitoneal, intravenous and intratumoral pathways of administration of rAAV vectors have been examined utilizing quantitative-PCR and immunohistochemical staining.
Outcomes: The very best transduction effectivity in metastatic cells in vivo was noticed 7 days after intranasal administration of a 1010 gc/0.03 ml dose of rAAV/DJ-CAG.
Conclusion: Melanoma gene remedy based mostly on rAAV vectors is a attainable remedy possibility.
Vector Competence of Aedes aegypti, Aedes albopictus and Culex quinquefasciatus from Brazil and New Caledonia for Three Zika Virus Lineages
Zika virus (ZIKV) has prompted extreme epidemics in South America starting in 2015, following its unfold via the Pacific. We comparatively assessed the vector competence of ten populations of Aedes aegypti and Ae. albopictus from Brazil and two of Ae. aegypti and one in all Culex quinquefasciatus from New Caledonia to transmit three ZIKV isolates belonging to African, Asian and American lineages.
Just lately colonized mosquitoes from eight distinct websites from each international locations have been orally challenged with the identical viral load (107 TCID50/mL) and examined after 7, 14 and 21 days. Cx. quinquefasciatus was refractory to an infection with all virus strains. In distinction, though competence assorted with geographical origin, Brazilian and New Caledonian Ae. aegypti may transmit the three ZIKV lineages, with a robust benefit for the African lineage (the one one reaching saliva one-week after problem).
Brazilian Ae. albopictus populations have been much less competent than Ae. aegypti populations. Ae. albopictus usually exhibited nearly no transmission for Asian and American lineages, however was environment friendly in transmitting the African ZIKV. Viral surveillance and mosquito management measures should be strengthened to keep away from the unfold of latest ZIKV lineages and decrease the transmission of viruses at the moment circulating.
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STJ97710 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Mouse monoclonal to IL-8. |
![]() |
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STJ97717 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Mouse monoclonal to IL-8. |
![]() |
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STJ97720 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Mouse monoclonal to IL-8. |
![]() |
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1730-8 | CORNING | 100/pk | EUR 88.8 |
Description: Disposable Plastic; Plastic Containers |
![]() |
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90258-A | BPS Bioscience | 5 µg | EUR 130 |
Description: Recombinant human Interleukin-8 is a disulfide-linked monomer protein consisting of 78 amino acid residues, migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Interleukin-8 mature chain was expressed in E. coli. |
![]() |
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90258-B | BPS Bioscience | 25 µg | EUR 205 |
Description: Recombinant human Interleukin-8 is a disulfide-linked monomer protein consisting of 78 amino acid residues, migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Interleukin-8 mature chain was expressed in E. coli. |
![]() |
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CT264 | U-CyTech | 0.5 mg | EUR 312 |
![]() |
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E5-00004 | EnoGene | 1mg | EUR 1152 |
![]() |
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A00423-1 | BosterBio | 100ul | EUR 476.4 |
Description: Mouse Monoclonal Antibody for IL-8 Antibody (CXCL8) detection. Tested with IHC in Human, Mouse, Rat. |
![]() |
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G065-8 | ABM | 200 reactions | EUR 200.4 |
![]() |
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Anti-CRBN | ImmunoStep | 50 µg | EUR 418.8 |
![]() |
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R00102-8 | BosterBio | 5ug/vial | EUR 310.8 |
Description: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. Swine IL-6 Recombinant Protein is purified interleukin-6 produced in yeast. |
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R00230-8 | BosterBio | 5ug/vial | EUR 310.8 |
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Swine IL-4 Recombinant Protein is purified interleukin-4 produced in yeast. |
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R00387-8 | BosterBio | 5ug/vial | EUR 310.8 |
Description: Interleukin-2 (IL-2) is a cytokine produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. Rabbit IL-2 Recombinant Protein is purified interleukin-2 produced in yeast. |
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R00421-8 | BosterBio | 5ug/vial | EUR 310.8 |
Description: IL-17A is a member of the IL-17 family of cytokines, whose members are involved in numerous immune regulatory functions. IL-17 induces the production of many other cytokines, chemokines, and prostaglandins. Swine IL-17A Recombinant Protein is purified interleukin-17A produced in yeast. |
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13102-05011 | AssayPro | 150 ug | EUR 248.4 |
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33486-05111 | AssayPro | 150 ug | EUR 313.2 |
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abx060803-25ug | Abbexa | 25 ug | EUR 644.4 |
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abx060804-25ug | Abbexa | 25 ug | EUR 644.4 |
![]() |
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P0180 | FN Test | 100ug | EUR 626.83 |
Description: Recombinant Human protein for IL-8 |
![]() |
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HY-P7224 | MedChemExpress | 50ug | EUR 596.4 |
![]() |
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SJB05-01 | Amyotop | 25µg/vial | EUR 342 |
![]() |
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8-E01A2155 | BlueGene |
|
|
Description: A competitive ELISA for quantitative measurement of Human THSD7a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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R00101-8 | BosterBio | 5ug/vial | EUR 310.8 |
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Ovine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast. |
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C5000-8 | Benchmark Scientific | 1 each | EUR 537.8 |
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STJ15100008 | St John's Laboratory | 250 µg | EUR 403.2 |
Description: These monoclonal antibodies enable sensitive and specific detection of bovine IL-8 in ELISpot. |
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STJ15100009 | St John's Laboratory | 250 µg | EUR 403.2 |
Description: This monoclonal antibody enables sensitive and specific detection of bovine IL-8 in ELISA. |
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RC222-19 | Bio Basic | 5ug | EUR 125.26 |
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5-01378 | CHI Scientific | 4 x 5mg | Ask for price |
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BF0238 | Affbiotech | 200ul | EUR 540 |
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E21-C97 | EnoGene | 10ug | EUR 411.6 |
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GT15156 | Neuromics | 100 ug | EUR 631.2 |
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H-2268.0001 | Bachem | 1.0mg | EUR 200.4 |
Description: Sum Formula: C45H66N18O7S; CAS# [138559-60-1] net |
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H-2268.0005 | Bachem | 5.0mg | EUR 691.2 |
Description: Sum Formula: C45H66N18O7S; CAS# [138559-60-1] net |
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H-2268.0025 | Bachem | 25.0mg | EUR 2648.4 |
Description: Sum Formula: C45H66N18O7S; CAS# [138559-60-1] net |
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QY-E60063 | Qayee Biotechnology | 96T | EUR 511.2 |
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R30420 | NSJ Bioreagents | 100 ug | EUR 419 |
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R31932 | NSJ Bioreagents | 100 ug | EUR 419 |
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F51235-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
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F51235-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
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5149-100 | Biovision | each | EUR 405.6 |
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abx195916-96tests | Abbexa | 96 tests | EUR 990 |
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201-12-0090 | SunredBio | 96 tests | EUR 528 |
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
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CSB-E04641h-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
Description: Quantitative sandwich ELISA kit for measuring Human Interleukin 8, IL-8 in samples from serum, cell culture supernates, saliva, urine, cerebrospinalfluid (CSF), tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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1-CSB-E04641h | Cusabio |
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Description: Quantitative sandwich ELISA kit for measuring Human Interleukin 8, IL-8 in samples from serum, cell culture supernates, saliva, urine, cerebrospinalfluid(CSF), tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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EH0205 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
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LF-EK60006 | Abfrontier | 1×96T | EUR 948 |
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GA-E0129HM-48T | GenAsia Biotech | 48T | EUR 346.8 |
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GA-E0129HM-96T | GenAsia Biotech | 96T | EUR 559.2 |
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QY-E04259 | Qayee Biotechnology | 96T | EUR 433.2 |
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YLA1210HU-48T | Shanghai YL Biotech | 48T | EUR 435 |
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YLA1210HU-96T | Shanghai YL Biotech | 96T | EUR 562.5 |
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CT212A | U-CyTech | 5-plate | EUR 554.4 |
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EHI0063 | Abclonal | 96Tests | EUR 625.2 |
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E410A07-100 | EnoGene | 100μg | EUR 1152 |
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EF003990 | Lifescience Market | 96 Tests | EUR 826.8 |
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LF-EK50165 | Abfrontier | 1×96T | EUR 777.6 |
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H-9625.0005 | Bachem | 5.0µg | EUR 194.4 |
Description: Sum Formula: C372H600N106O106S4; CAS# [142298-00-8] |
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H-9625.0025 | Bachem | 25.0µg | EUR 457.2 |
Description: Sum Formula: C372H600N106O106S4; CAS# [142298-00-8] |
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HY-P7380 | MedChemExpress | 50ug | EUR 596.4 |
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H-3742.0010 | Bachem | 10.0µg | EUR 340.8 |
Description: Sum Formula: C397H644N114O111S4; CAS# [142298-01-9] |
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H-3742.0050 | Bachem | 50.0µg | EUR 1167.6 |
Description: Sum Formula: C397H644N114O111S4; CAS# [142298-01-9] |
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RP00052 | Abclonal | 5 μg | EUR 178.8 |
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K4169-100 | Biovision | each | EUR 874.8 |
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QY-E60102 | Qayee Biotechnology | 96T | EUR 511.2 |
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SPXPR-8 | Scientific Laboratory Supplies | 1ML | EUR 249.66 |
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RC242-19 | Bio Basic | 5ug | EUR 125.26 |
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RC282-19 | Bio Basic | 5ug | EUR 125.26 |
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QY-E120050 | Qayee Biotechnology | 96T | EUR 573.6 |
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13102-05021 | AssayPro | 150 ug | EUR 313.2 |
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CC97-10ug | Novoprotein | 10ug | EUR 175.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
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CC97-1mg | Novoprotein | 1mg | EUR 2739.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
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CC97-500ug | Novoprotein | 500ug | EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
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CC97-50ug | Novoprotein | 50ug | EUR 406.8 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
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C035-10ug | Novoprotein | 10ug | EUR 181.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
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C035-1mg | Novoprotein | 1mg | EUR 2203.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
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C035-500ug | Novoprotein | 500ug | EUR 1557.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
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C035-50ug | Novoprotein | 50ug | EUR 424.8 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
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C037-10ug | Novoprotein | 10ug | EUR 181.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
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C037-1mg | Novoprotein | 1mg | EUR 2203.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
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C037-500ug | Novoprotein | 500ug | EUR 1557.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
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C037-50ug | Novoprotein | 50ug | EUR 412.8 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
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E-CL-H0048 | Elabscience Biotech | 1 plate of 96 wells | EUR 700.8 |
Description: A sandwich CLIA kit for quantitative measurement of Human IL-8 (Interleukin 8) in samples from Serum, Plasma, Cell supernatant |
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E-EL-H0048 | Elabscience Biotech | 1 plate of 96 wells | EUR 452.4 |
Description: A sandwich ELISA kit for quantitative measurement of Human IL-8 (Interleukin 8) in samples from Serum, Plasma, Cell supernatant |
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EI1008-1 | AssayPro | 96 Well Plate | EUR 572.4 |
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EK0240 | SAB | 96 tests | EUR 723.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Interleukin 8,IL-8 in samples from serum, plasma, tissue homogenates and other biological fluids. |
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RC212-19A | Bio Basic | 5ug | EUR 125.26 |
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RC212-19B | Bio Basic | 5ug | EUR 125.26 |
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ECMJ-8 | Scientific Laboratory Supplies | EACH | EUR 295.26 |
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GR109009 | Genorise Scientific | 50 mg | EUR 477.6 |
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41063-100ul | SAB | 100ul | EUR 302.4 |
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41063-50ul | SAB | 50ul | EUR 224.4 |
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40-331-0005mg | ProSci | 0.005 mg | EUR 311.1 |
Description: IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues. |
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40-331-0025mg | ProSci | 0.025 mg | EUR 437.1 |
Description: IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues. |
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90-492 | ProSci | 10 ug | EUR 405.6 |
Description: Interleukin-8 (IL-8) was originally discovered as a neutrophil chemotactic and activating factor and is a member of the alpha (CXC) subfamily of chemokines (including also platelet factor 4, GRO, IP-10, etc.). Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes and various tumor cell lines, produce IL-8 in response to a wide variety of proinflammatory stimuli such as exposure to IL-1, TNF, LPS and viruses. IL-8 has a wide range of other proinflammatory effects. It is a potent chemoattractant for neutrophils and causes degranulation of neutrophil specific granules and azurophilic granules. IL-8 induces expression of the cell adhesion molecules CD11/CD18 and enhances the adherence of neutrophils to endothelial cells and subendothelial matrix proteins. Besides neutrophils, IL-8 is also chemotactic for basophils, T cells and eosinophils. IL-8 has been reported to be a co-mitogen for keratinocytes and was also shown to be an autocrine growth factor for melanoma cells. IL-8 was also reported to be angiogenic both in vivo and in vitro. |
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90-493 | ProSci | 50 ug | EUR 789.9 |
Description: Interleukin-8 (IL-8) was originally discovered as a neutrophil chemotactic and activating factor and is a member of the alpha (CXC) subfamily of chemokines (including also platelet factor 4, GRO, IP-10, etc.). Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes and various tumor cell lines, produce IL-8 in response to a wide variety of proinflammatory stimuli such as exposure to IL-1, TNF, LPS and viruses. IL-8 has a wide range of other proinflammatory effects. It is a potent chemoattractant for neutrophils and causes degranulation of neutrophil specific granules and azurophilic granules. IL-8 induces expression of the cell adhesion molecules CD11/CD18 and enhances the adherence of neutrophils to endothelial cells and subendothelial matrix proteins. Besides neutrophils, IL-8 is also chemotactic for basophils, T cells and eosinophils. IL-8 has been reported to be a co-mitogen for keratinocytes and was also shown to be an autocrine growth factor for melanoma cells. IL-8 was also reported to be angiogenic both in vivo and in vitro. |
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91-026 | ProSci | 0.05 mg | EUR 651.3 |
Description: Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states. |
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91-028 | ProSci | 0.05 mg | EUR 619.8 |
Description: Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states. |
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ABP52884-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human IL-8 |
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ABP52884-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human IL-8 |
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ABP52884-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human IL-8 |
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ABP54886-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8 |
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ABP54886-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8 |
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ABP54886-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8 |
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ABP51621-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8 |
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ABP51621-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8 |
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ABP51621-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8 |
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APR00274G | Leading Biology | 0.1mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IL-8 . This antibody is tested and proven to work in the following applications: |
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BF0238-BP | Affbiotech | 1mg | EUR 234 |
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ES2620-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against IL-8 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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ES2620-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against IL-8 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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ES3883-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against IL-8 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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ES3883-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against IL-8 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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MO15072 | Neuromics | 500 ug | EUR 1092 |
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MO15073 | Neuromics | 100 ug | EUR 568.8 |